Many people believe that something about our individual minds—a soul, if you will—lives on even after the brain has disintegrated. Ultimately, they see the mind as a function of a soul that survives death, rather than as a function of a brain. But if a nonmaterial soul is really the seat of the mind, why do you even need a brain? What is left for the brain to do? Some propose that the brain is simply an interface to the body. But science has shown that it is the brain that is in charge. In this article, Merle Hertzler lays out the evidence that we think with our brains, not with immaterial souls. And the possibility of bodily resurrection doesn't fare much better. So we need to make the most of the one life that we know for sure exists because odds are, that's the only life that any of us are going to get.