In this paper John W. Loftus shares ten helpful tips on trying to change the minds of Christian believers based on his nearly 20 years of experience engaging in it. He reviews the most common cognitive biases that one bumps against in the attempt to plant seeds of doubt, and notes some of the most pointed questions that one can ask to really get to the heart of the matter. This includes highlighting particular facts about the world that simply cannot be reasonably squared with traditional Christian beliefs. Even if your attempts result in a low rate of success, Loftus argues, every mind changed amounts to less religious harm in the world than there would have been otherwise, and the results of an attempt can reveal rather eye-opening truths even when it is not successful.